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About Viagra

Sildenafil citrate, sold as Viagra, Revatio and under various other trade names, is a drug used to treat erectile dysfunction and pulmonary arterial hypertension (PAH). It was originally developed by British scientists and then brought to market by the US-based pharmaceutical company Pfizer. It acts by inhibiting cGMP-specific phosphodiesterase type 5, an enzyme that delays degradation of cGMP, which regulates blood flow in the penis. Since becoming available in 1998, sildenafil has been the prime treatment for erectile dysfunction; its primary competitors on the market are tadalafil (Cialis) and vardenafil (Levitra).

The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Its use is now standard treatment for erectile dysfunction in all settings, including diabetes. People on antidepressants may experience sexual dysfunction, either as a result of their illness or as a result of their treatment. A 2003 study showed that sildenafil improved sexual function in men in this situation. Following up to earlier reports from 1999, the same researchers found that sildenafil was able to improve sexual function in female patients on antidepressants as well.

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Skelaxin
Skelaxin
Active Ingredient: Metaxalone
Skelaxin is a muscle relaxant. It works by blocking nerve impulses (or pain sensations) in the brain. Skelaxin is used together with rest and physical therapy to treat discomfort associated with acute skeletal muscle conditions such as pain or injury.
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Skelaxin 400mg
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  • INDICATIONS

    Skelaxin (metaxalone) is indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions.

    INSTRUCTIONS

    Take Skelaxin exactly as prescribed by your doctor.

    The recommended dose for adults and children over 12 years  is one 800 mg tablet three to four times a day.

    Ask your health care provider any questions you may have about how to use Skelaxin.

    STORAGE

    Store Skelaxin at Controlled Room Temperature, between 15°C and 30°C (59°F and 86°F). Keep Skelaxin out of the reach of children.F and 86

    MORE INFO:

    Active Ingredient: Metaxalone

    • Skelaxin may enhance the effects of alcohol and other CNS depressants.
    • Metaxalone should be administered with great care to patients with pre-existing liver damage. Serial liver function studies should be performed in these patients.
    • Taking  Skelaxin with food may enhance general CNS depression; elderly patients may be especially susceptible to this CNS effect.
    • The carcinogenic potential of metaxalone has not been determined.
    • Metaxalone tablets should not be used in women who are or may become pregnant and particularly during early pregnancy unless, in the judgement of the physician, the potential benefits outweigh the possible hazards.
    • It is not known whether this drug is secreted in human milk. As a general rule, nursing should not be undertaken while a patient is on a drug since many drugs are excreted in human milk.
    • Safety and effectiveness in children of 12 years  and below have not been established. 
  • The most frequent reactions to metaxalone include:

    CNS: drowsiness, dizziness, headache, and nervousness or "irritability";

    Digestive: nausea, vomiting, gastrointestinal upset.

    Other adverse reactions are:

    Immune System: hypersensitivity reaction, rash with or without pruritus;

    Hematologic: leukopenia; hemolytic anemia;

    Hepatobiliary: jaundice.

    Though rare, anaphylactoid reactions have been reported with metaxalone.