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About Viagra

Sildenafil citrate, sold as Viagra, Revatio and under various other trade names, is a drug used to treat erectile dysfunction and pulmonary arterial hypertension (PAH). It was originally developed by British scientists and then brought to market by the US-based pharmaceutical company Pfizer. It acts by inhibiting cGMP-specific phosphodiesterase type 5, an enzyme that delays degradation of cGMP, which regulates blood flow in the penis. Since becoming available in 1998, sildenafil has been the prime treatment for erectile dysfunction; its primary competitors on the market are tadalafil (Cialis) and vardenafil (Levitra).

The primary indication of sildenafil is treatment of erectile dysfunction (inability to sustain a satisfactory erection to complete intercourse). Its use is now standard treatment for erectile dysfunction in all settings, including diabetes. People on antidepressants may experience sexual dysfunction, either as a result of their illness or as a result of their treatment. A 2003 study showed that sildenafil improved sexual function in men in this situation. Following up to earlier reports from 1999, the same researchers found that sildenafil was able to improve sexual function in female patients on antidepressants as well.

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Imdur (Isosorbide mononitrate)
Imdur
Active Ingredient: Isosorbide Mononitrate
Imdur is used to prevent angina attacks (chest pain).
Other names for this medication:
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  • INDICATIONS

    Imdur (isosorbide mononitrate) is in a group of drugs called nitrates. It dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.

    INSTRUCTIONS

    Take Imdur exactly as prescribed by your doctor.

    Take this medication with at least 4 ounces of water or other liquid. Do not crush, chew, or break an extended-release tablet. Swallow the pill whole.

    If possible, try to rest or stay seated when you use this medication. Imdur can cause dizziness or fainting. Use Imdur regularly to prevent an angina attack.

    Do not stop taking Imdur suddenly. Stopping suddenly could cause a severe angina attack.

    DOSAGE

    The usual adult dose of Imdur is 30-60 mg orally once a day. Follow your doctor's dosing instructions very carefully.

    STORAGE 

    Store this medicine at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use.

  • Do not use Imdur if you are taking sildenafil (Viagra, Revatio). A dangerous drug interaction could occur, leading to serious side effects. You should not use Imdur if you are allergic to isosorbide mononitrate, isosorbide dinitrate, (Isordil, Dilatrate, Isochron), or nitroglycerin, or if you have early signs of a heart attack (chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling).

    To make sure you can safely take Imdur, tell your doctor if you have any of these other conditions:

    congestive heart failure;
    low blood pressure; or
    kidney disease.

    Tell your doctor about all other medications you use, especially:

    blood pressure medication;
    dihydroergotamine (D.H.E. 45, Migranal) or ergotamine (Ergomar, Cafergot, and others);
    an erectile dysfunction medication such as tadalafil (Cialis) or vardenafil (Levitra);
    a beta blocker such as atenolol (Tenormin, Tenoretic), carvedilol (Coreg), labetalol (Normodyne, Trandate), metoprolol (Dutoprol, Lopressor, Toprol), nadolol (Corgard), propranolol (Inderal, InnoPran), sotalol (Betapace), and others;
    heart or blood pressure medicine such as amlodipine (Norvasc, Caduet, Exforge, Lotrel, Tekamlo, Tribenzor, Twynsta, Amturnide), diltiazem (Cartia, Cardizem), nifedipine (Nifedical, Procardia), verapamil (Calan, Covera, Isoptin, Verelan), and others.

    It is not known whether Imdur will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. It is not known whether isosorbide mononitrate passes into breast milk or if it could harm a nursing baby. Do not use Imdur without telling your doctor if you are breast-feeding a baby.

  • Call your doctor at once if you have a serious side effect such as:

    fast, slow, pounding, or uneven heart rate;
    feeling like you might pass out;
    trouble breathing, blue-colored skin, tired feeling; or
    worsening angina pain.

    Less serious Imdur side effects may include:

    headache, mild dizziness;
    warmth, redness, or tingling under your skin;
    nausea, vomiting, constipation, diarrhea;
    pain or stiffness in joints or muscles;
    hot flashes; or
    dry mouth.