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Baclofen

Baclofen
Baclofen is a muscle relaxant drug. Baclofen reduces the severity of muscular spasms in neurological conditions like multiple sclerosis. It also reduces frequency of muscle spasms in multiple sclerosis.
Baclofen 25mg
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25mg × 90 pills $2.43$218.61$102.87+ Cialis
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Baclofen 10mg
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10mg × 270 pills $0.71$190.36$57.93+ Viagra
10mg × 360 pills $0.69$248.29$82.76+ Cialis
  • INDICATIONS

    Baclofen is used for treating spasm of skeletal muscles that cause muscle clonus, rigidity, and pain due to multiple sclerosis. Baclofen relaxes skeletal muscles, the muscles that move the skeleton (also called striated muscle). Chemically, Baclofen is related to gamma-aminobutyric acid (GABA), a naturally-occurring neurotransmitter in the brain. Neurotransmitters are chemicals that nerves use to communicate with one another. GABA released by some nerves causes the activity of other nerves to decrease. It is believed that Baclofen, acting like GABA, blocks the activity of nerves within the part of the brain that controls the contraction and relaxation of skeletal muscle. Baclofen was approved by the FDA in November, 1977.

    INSTRUCTIONS

    The usual starting dose of Baclofen for adults is 5 mg three times daily. Based on the response, the dose can be increased gradually every three days to a maximum of 80 mg/day in several doses.

    STORAGE

    Baclofen should be stored between 15°C (59°F) and 30°C (86°F). Keep Baclofen out of the reach of children.

  • Use of Baclofen with other drugs that also depress the function of nerves may lead to additional reduction in brain function.

    In addition to the risk of depressing brain function, the use of Baclofen and tricyclic antidepressants (e.g., Elavil, Sinequan) together may cause muscle weakness.

    Use of Baclofen and monoamine oxidase inhibitors (e.g. Nardil, Parnate) can result in greater depression of brain function as well as low blood pressure.

    As Baclofen can increase blood sugar, doses of antidiabetic drugs may need to be adjusted when Baclofen is taken.

    The use of Baclofen by pregnant women has not been evaluated.

    Baclofen can be detected in the breast milk of mothers taking oral Baclofen. No information is available on the presence of Baclofen in the breast milk of mothers receiving Baclofen intrathecally.

  • Baclofen may cause drowsiness, weakness, dizziness, headache, seizures, nausea, vomiting, low blood pressure, constipation, confusion, respiratory depression, inability to sleep, and increased urinary frequency or urinary retention.

    Abrupt discontinuation of oral Baclofen may cause seizures and hallucinations. Abrupt discontinuation of intrathecal Baclofen may result in high fever, rebound spasticity, muscle rigidity, and rhabdomyolysis (muscle breakdown).

About Cialis

Cialis is an oral drug for male impotence, also known as erectile dysfunction (ED). It works by dilating blood vessels in the penis, allowing the inflow of blood needed for an erection.

Cialis causes erections only during sexual excitement. It does not work in the absence of arousal and does not increase sexual desire.

In December 2003, the Food and Drug Administration approved Cialis for sale in the United States as the third ED prescription drug pill (after sildenafil (Viagra) and vardenafil (Levitra)). Cialis 48-hour effectiveness earned it the nickname, "The Weekend Pill"; like sildenafil and vardenafil, tadalafil is recommended as an 'as needed' medication. Cialis is the only one of the three that is also offered as a once-daily medication.

Moreover, Cialis was approved in May 2009 in the United States for the treatment of pulmonary arterial hypertension and is currently under regulatory review in other regions for this condition.

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